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World of the Large Steam Sterilizers

Our large autoclaves
For large sterilization volume.

You need to reprocess large quantities of sterilized items efficiently and reliably? Our large autoclaves with an capacity of up to 200 litres meet every requirement in practices, clinics and hospitals.

Cliniclave 45

Cliniclave 45

Compact, fast, economical. The large autoclave with 105 liters for reprocessing a sterilization unit in the shortest possible time.

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Cliniclave 45 M

Cliniclave 45 M

The M stands for Magnum: The large 200-liter autoclave sterilizes up to two STE or 70 kg load in record time.

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Cliniclave 45 D

Cliniclave 45 D

Innovative device concept with pass-through: The double-door large autoclave with 110 litres meets the highest demands for infection control.

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Cliniclave 45 MD

Cliniclave 45 MD

Make the impossible possible: The double-door large autoclave with 205 litres guarantees optimal sterilization processes for 2 STE or 70 kg load.

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Vacuclave 550

Think BIG: The large small autoclave with 50 litres and trend-setting product highlights.

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Accessories

As versatile as you: Find the right accessories for you. And for your MELAG large steam sterilizer.

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Expert guidance - just for You.

Get in touch with our international MELAG hygiene experts: We’re here to advise you personally and help you find the best hygiene solution tailored to your requirements.

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C45 Accordion Modul Routine-Prüfung
Routine Testing

Trust is good. Control is better.

Based on international standards MELAG recommends the performance of routine checks to ensure the safe operation of a large steam sterilizer.

A Bowie & Dick test serves as proof of the steam penetration of porous materials such as textiles. Simply enter the test package in the large steam sterilizer and start the corresponding Bowie & Dick test program. The Bowie & Dick test provides proof of fast and equal steam penetration into the test package. Please perform the Bowie & Dick test daily and additionally the vacuum test monthly.


An additional batch control can be performed on critical B instruments using a MELAcontrol Helix test body. Our MELAcontrol Helix system enables you to perform safe and reliable checks of the sterilization process even in complex hollow body articles. The colour change of the indicator strips makes for verifiable documentation of the batch approval performed on the XXL colour touch-display, thereby obviating the need for storage of the Helix test body indicator strips in a paper archive.

The supply of the large steam sterilizer with demineralized water can be performed using an external water treatment unit such as the MELAdem 56 reverse osmosis unit from MELAG. Irrespective of your choice of water treatment unit, MELAG Cliniclave 45 series devices are one of the few large steam sterilizers available on the market which comply with the requirements placed on the protection of the drinking water supply by EN1717.

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Support & Contact

You have questions? We the answers!

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Reprocessing in XXL

Sterilization in large clinics, hospitals and CSSD

Large steam sterilizers are ideal for large practices, outpatient surgery centers, day clinics, medical care centers and smaller hospitals. Whether for 1 StU or 2 StU, as a single-door or double-door unit variant - every Cliniclave 45 is equipped with the same innovative future-oriented technology. This enables safe and efficient sterilization, tailored to the individual needs depending on the number of patients, variety of instruments, spatial situation, regional standards and guidelines.

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Integrated software for documentation and approval

With ProControl, you can provide proof of error-free instrument sterilization in a quick, reliable and paperless way. Because batch approval is performed directly on the display and log storage via CF card or network.

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Record operating times thanks to double jacket technology

Maximum safety in minimum time? That is exactly what the patented double chamber technology ensures. A MELAG patent since 2012. Sterilize partial loads in approx. 20 min. and full loads in approx. 35 min. (excl. drying) with the highest saturated steam quality.

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Optimum drying results with DRYtelligence

No more wet instruments after sterilization? Then benefit from the DRYtelligence algorithm-controlled drying. Intelligent drying ensures optimum drying results and at the same time reduces drying time by up to 80%.

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All-round flexibility with high loading capacities

Made for big tasks: So that every practice or clinic can organize the workflow in the way that suits it best, the Cliniclave 45 Series not only offers outstanding loading capacities of up to 70 kg, but also a wide range of loading options.

Autoclave Reviews

Enthusiastic customers. For more than 75 years.

More than a seal of quality: Your trust confirms our passion for quality, reliability, and service—in practices and clinics worldwide.

4,9

54 Customer Reviews

1

Reviews by Customers

Dentists Hasenhoeheverified

Exclusive advice, convincing quality. Absolutely recommendable!

Wonderful! Received exclusive advice from Mr Trapper today. Tested great Melag appliances....and bought them. Thank you very much! We will recommend you to others.

Dr Gebhardt, Biss45verified

System solution from MELAG

We rely on an autoclave, a sealing device and a thermal disinfector from MELAG for reprocessing. The optimally harmonised system ensures uniform operation and enables new colleagues to be quickly trained. If we have any questions or uncertainties, MELAG support is always on hand to provide reliable assistance.

Tree child fiveverified

Reliable products and outstanding support

Melag is a very nice company. The products seem well thought out and reliable and the service department is also easy to contact and helpful if you have any questions. All in all, a very positive experience.

Dental team in Zehlendorfverified

MELAtherm and Vacuklav - the best combination for us

For us, MELAtherm and Vacuklav simply belong together. The combination gives us a consistently safe feeling in our day-to-day work because our processes are clearly structured and the instruments are reprocessed reliably. With the MELAG system, we know that we can guarantee maximum safety for our patients at all times.

Uwe Johannesverified

Top device with best service

Melag 40 B+ Evolution...best appliance, shortest programme times, best service.

Wendt Dentalverified

Successful switch to the Vacuklav 40B+ Evolution

After 16 years, the old Melag Vacuklav 40B has had its day and has been replaced by its successor, the Melag Vacuklav 40B+ Evolution!

Teufen Eye Clinicverified

Melag autoclaves for the highest hygiene standards

The Teufen Eye Clinic is one of the leading private eye clinics in Switzerland. The autoclaves from MELAG meet the high medical standards of our ophthalmologists and contribute to top hygiene in our clinic.

Specialist Konstantinos Jiouchasverified

Efficient sterilisation thanks to the intuitive Vacuclave 318

With the Vacuclave 318 from MELAG, the instruments used are sterilised with maximum efficiency. The sophisticated technology is also noticeable in the intuitive operation of the display.

Dr Rebaverified

MELAG: Top quality and service since the practice was founded

The sterilisation products from MELAG have been part of our equipment since the practice was founded: top quality and service!

Fabian Steinwedeverified

Once MELAG always MELAG

Once MELAG always MELAG - the price-performance ratio of the new MELAG autoclaves is top!

Dr Helfried Fischerverified

Environmentally friendly and economical: 50-litre autoclave

The new 50 litre autoclave combines environmental protection with economic efficiency. Thanks to short, energy-efficient and high-performance reprocessing processes, we can reprocess our instruments sustainably and safely in a short time.

Dr Rousiverified

ProDentist recommends MELAG autoclaves

We at ProDentist also recommend the high-quality autoclaves from MELAG to other practices to ensure reliable reprocessing between treatments

ENT med. northverified

MELAG system solution: the basis for smooth processes

Instrument reprocessing with the MELAG system solution forms the basis for smooth practice processes!

Practice clinic Schillerstrasseverified

Satisfied MELAg customers for years

Our practice has been a satisfied customer of MELAG for many years! With the high-quality sterilisation products, we can ensure that sterility is consistently maintained in our practice.

Sandnes Emergency Centreverified

Safe, fast sterilisation with Cliniclave 45

We need safe and fast sterilisation of instruments for emergency treatments - that's why we chose Cliniclave 45 from MELAG.

Berger Clinicverified

More efficiency and well-being thanks to MELAg autoclaves

The fast and safe sterilisation of more instruments leads to greater efficiency and patient well-being. We are fully convinced by the MELAG autoclaves.

Medeco Dental Clinicverified

Cliniclave 45. faster, more efficient, less effort

We are very happy that we decided in favour of the Cliniclave 45. We work faster, more efficiently and with much less effort than before.

Drs Voigt & Weickardtverified

Compact MELAG autoclave: space-saving and fast

A space-saving and fast helper in the reprocessing room: we love our compact MELAG autoclave.

Daniel Talanovverified

Patient safety thanks to MELAG autoclave

We attach great importance to patient safety, which is why we use MELAG products for instrument reprocessing. The premium class autoclave in particular impresses with the fastest programme run times.

West Coast Dental Clinicverified

MELAG: Quality and fast cycles

We have opted for the high quality of MELAG products. They fulfil our requirements perfectly every day - especially with the fast cycles of the premium class

Dr. Kayla Tehverified

MELAG System Solution - Made in Germany 🇩🇪

With the Vacuclave and the MELAtherm, we have made exactly the right choice for our premium approach in our dental practice. The devices are reliable and durable. Compared to other models we have used before, we can rely on the system completely. There are no unplanned breakdowns. In addition, the MELAG team is always easy for us to contact. So if you are looking for the highest quality standards, you can't go past MELAG.

Christian Rötheverified

Expertise and service you can rely on, including durable devices

Top company, always nice, always competent, appliances very reliable, last forever, maintenance costs moderate.

Tünni Roppelverified

Top support and technology

We have always been satisfied, especially the technical support has always been flawless!

Dipl.-Med. Annette Müllerverified

Safe, time-saving, simple - Melag convinces

Safety, great time savings, simple operation. We are convinced by the MELAG system solution with Vacuclave and MELAtherm.

Sindy Burrowverified

Great company with great employees

MELAG has been with me for many years. Working together is always fun - you guys are great! Keep up the good work.

Vitaliy Kolofiy from MVKverified

We have been using MELAG thermal disinfectors, autoclaves and sealing devices in our nail studios for many years now

Whether in Krakow, Wroclaw, Vienna or Berlin, in the MVK studios modern nail design goes hand in hand with safe hygiene - thanks to the MELAG system solution!

Andrea Königsberger (Podiatrist)verified

A big compliment for the production in Berlin

I had the opportunity to visit the production site in Berlin and was really impressed by its size and professionalism. The employees radiate a palpable enthusiasm for the subject of instrument reprocessing. Please keep up the good work!

MKG practice GesichtsPunktverified

Super concept with the MELAG system solution

We have a very high throughput of instruments in our oral and maxillofacial practice. This makes it all the more important for us to be able to rely on our instrument reprocessing equipment at all times. We use two MELAtherm, a Vacuklav and a large Cliniclave 45 steriliser every day. We are very satisfied with the entire system and appreciate the reliability of the products in everyday practice.

Hottelmann dental galleryverified

I appreciate the reliability and simple operation of MELAG appliances.

Reni Otte, Podiatristverified

Instrument reprocessing in minimal space

Our processing room is very small, so space-saving and reliable solutions were all the more important to us. With the Vacuklav and the MELAtherm, we have found exactly the right appliances to implement optimum hygiene processes in a minimum of space. We would choose MELAG again at any time.

Dr Christoph Hobergverified

Preparation process optimised with MELAG

With MELAtherm and MELAstore and our MELAG autoclaves, we are able to reprocess large quantities of instruments in our orthodontic practice quickly, cost-effectively and, above all, safely.

May & Thannhäuserverified

Sterilisation and packaging: all-round safety

After quick and safe packaging with the MELAseal sealing device, we take care of sterilisation in the Vacuklav. The perfectly harmonised MELAG system guarantees an efficient hygiene chain.

Southpaws Veterinary Clinicverified

MELAtherm and Cliniclave 45 - The ideal duo for our veterinary clinic

The MELAG washer-disinfector and large autoclave ensure a high level of infection prevention and the best possible protection for both animals and humans. I truly appreciate the German quality and MELAG’s strong specialization in the field of instrument reprocessing.

Smart Dental Clinic Teamverified

An investment that pays off in everyday life

The interaction between MELAtherm, MELAseal and our Vacuclave makes a huge difference. No isolated solutions, but a harmonised workflow. You can tell that the system has been designed holistically. My team particularly appreciates the ease of use and the reliability of the process. We would choose MELAG again at any time.

Elena Barraquerverified

I didn't know sterilisation was so quick!

We are absolutely delighted with our new small autoclave from MELAG. The cycle times are significantly faster compared to our previous model, which makes our day-to-day work much easier. A clear recommendation to buy!

Haruplant Dental Clinicverified

We have 3 MELAG autoclaves in use

Our clinic in South Korea has a strong focus on surgical treatments. In order to reliably guarantee our high throughput, we have opted for a system with three MELAG autoclaves - with a large load volume and fast cycle times. I fully support this system and can recommend the products to every practice and clinic without reservation.

Fujimoto Dental Clinicverified

I am Shinji Fujimoto, Director of the Fujimoto Dental Clinic in Yamaguchi, Japan. In our practice, we attach great importance to prevention, personalised care and transparent communication - this also includes a consistent infection prevention concept.

With the MELAG system solutions, we fulfil the highest safety standards in accordance with RKI guidelines. The thermal disinfectors ensure reliable cleaning and disinfection of our surgical instruments, while the Professional class autoclaves and the MELAquick guarantee safe class B sterilisation. The integrated documentation also makes our day-to-day work in the practice easier.

Dr. Duval Aloush from Dubaiverified

From the best, for the best: Dr Duval trusts the MELAG system solution, manufactured with 100% German quality, to ensure outstanding workflows and safe treatments.

Dental clinic Zafrillaverified

Efficiency and safety at the highest level

At Clínica Dental Zafrilla we offer a wide range of treatments, from prophylaxis to sophisticated aesthetic procedures. To ensure complete and safe sterilisation of our instruments at all times, we need powerful and reliable technology.

With the MELAG Vacuclave, we have found just that. Modern vacuum technology guarantees complete and reliable sterilisation of all instruments. We particularly appreciate the fast cycle times, which make our reprocessing processes more efficient and significantly reduce waiting times.

Oriana Clinicverified

2x MELAtherm, 2x Cliniclave

We decided in favour of MELAG after intensive research and due to the many positive responses from the medical sector - and would make this decision again at any time.

The devices impress with their high reliability and simple, intuitive operation. It is extremely important to be able to rely 100% on your technology, especially in the stressful day-to-day running of a practice. This is exactly the case here. No unnecessary complications, no failures - simply constant performance at the highest level.

For us, the MELAG system is clearly the "gold standard" in the field of hygiene and sterilisation. Anyone who values quality, safety and durability will definitely not go wrong here. A clear recommendation to buy!

HappyCab in Saint Priestverified

Highest hygiene standards for modern orthodontics

Our innovative HappyCab orthodontics centre in Saint-Priest not only stands for a modern, aesthetic design, but above all for an uncompromising hygiene concept. As the management, it was particularly important to me to rely on high-performance and absolutely reliable technology in our sterilisation.

With two Cliniclave 45 autoclaves and two MELAtherm 10 thermal disinfectors, we have made exactly the right decision. The Cliniclave 45 enables us to sterilise large quantities of instruments quickly and safely, while the MELAtherm 10 ensures thorough cleaning and disinfection.

This combination not only gives us maximum safety for our patients, but also supports our entire team in maintaining the highest standards of hygiene on a daily basis. For us, the system is a central component of our quality promise.

Unident Union Dental Spa verified

With the aligned devices of the MELAG System Solution, our patients and the entire team are perfectly protected.

Janine Booksverified

Sehr zufrieden mit unserem MELAG Autoklaven

Our old autoclave broke down. The replacement was delivered relatively quickly by the depot and the instruction was comprehensive. We are very satisfied with the first impression of our new MELAG autoclave.

Dr. Tranverified

Dr. Daniel Tan & Associatesverified

Our commitment is to provide the highest standard of infection prevention and best personalised care for our patients.

We no longer wanted individual solutions, but a system that works as a unit. With MELAG we have found exactly that. The thermal disinfector, the sealing device and the autoclave fit together perfectly. This saves time, reduces sources of error and ensures process clarity. Particularly practical: everything looks "out of one mould". My team loves this structure.

Denta-Medica Dental Clinic verified

Workflow on a new level

We deliberately wanted to move away from individual stand-alone solutions and towards a well thought-out overall system. With MELAG, we have found exactly that. The thermal disinfector, sealing device and autoclave are perfectly harmonised with each other and interlock seamlessly. This saves valuable time, minimises sources of error and creates clear, reliable processes in everyday life. It is particularly pleasant that everything seems to come from a single source. My team really appreciates this clear structure.

Dr. Nagamineverified

MELAG Autoclave & Washer-Disinfector❤️

I am Dr Kensaku Nagamine and I founded the Nagamine Dental Clinic in Hokkaido, Japan, in 2021. As we treat patients of all ages, efficient processes and reliable infection prevention are particularly important to us.

We rely entirely on system solutions from MELAG. The MELAtherm enables us to clean and disinfect our instruments quickly and safely, and the MELAG class B autoclaves ensure reliable sterilisation. The simple operation and integrated documentation make our day-to-day work at the practice much easier.

Thanks to MELAG, we can reduce waiting times, work efficiently and maintain the highest standards of hygiene. This gives us more time for the essentials: the personalised and safe treatment of our patients.

Dr Florin Lazarescuverified

Hygiene processes are now centralised in our practice workflow

Space constraints, staff turnover and constant time pressure in our daily practice make it essential for us to ensure that every process runs smoothly. This is where the MELAG system, consisting of a sealing unit, an autoclave and a thermal disinfector, comes in.

The workflows are perfectly coordinated - from loading and short cycle times to complex processing concepts. This saves us precious time every day and reduces errors, especially when training new employees.

MELAG is fully co-operative and provides us with optimum support. The system provides us with security, structure and efficiency throughout the entire training process."

University of Sarajevoverified

MELAG also impresses at our university

Since 2019, the Faculty of Stomatology at the University of Sarajevo has fundamentally modernised its CSSD and opted entirely for a system from MELAG - a move that has paid off in every respect. With 8 MELAtherm, 8 Vacuklav, 3 Cliniclave 45 M and 3 MELAseal rotary sealers, a high-performance, perfectly harmonised infrastructure has been created. The cleaning and sterilisation processes now run reliably, reproducibly and much more efficiently.

The consistent performance of the devices is particularly impressive: every cycle fulfils the highest hygiene standards and gives the team maximum safety. At the same time, throughput times have been noticeably reduced, which considerably eases the burden on internal processes and allows more focus on teaching and patient care. Despite the high number of devices, the CSSD remains optimally organised and structured to save space thanks to the well thought-out, compact design. The investment is also economically sustainable - thanks to its robust design, low downtimes and long-term operational reliability.

Dr Cesare Parisverified

Top hygiene processes - made in Germany ⭐⭐⭐⭐⭐

With several treatment rooms and eight practitioners, efficient, safe workflows and absolutely reliable technical equipment are essential. This is precisely where the practice consistently relies on MELAG. Thanks to the sophisticated system solution, instruments are reprocessed in accordance with the highest hygiene standards, ensuring smooth processes in everyday practice. For Dr Cesare Paris, the protection of patients is the top priority - as is the safety of the entire team. With the MELAG devices, the practice can guarantee a high level of quality and safety at all times and work efficiently at the same time.

Prosthodontic Associatesverified

The MELAG System Solution streamlines our instrument decontamination process considerably.

Since we started using the MELAG system, our entire instrument reprocessing has become significantly more efficient and safer - without any additional organisational effort. The intuitive user interfaces and fast cycle times of the MELAG steam sterilisers and the thermal disinfector allow us to invest more time in treating our patients.

Our reprocessing room is equipped with a fully validated system solution: The MELAtherm takes care of the automatic cleaning and disinfection of our instruments, offering the highest level of infection protection for patients and the team. The cleaning and drying results impress us every day. The MELAseal rotary sealing device ensures that our medical devices are packaged safely and in accordance with standards. Two premium-class steam sterilisers ensure reliable sterilisation.

Water treatment via MELAdem is also reliable and space-saving - quality or storage problems are a thing of the past. With the MELAtrace documentation software, all processes are mapped in a legally compliant manner: Each batch is automatically documented, released and archived as a bundled PDF. Barcode labels also enable seamless traceability back to our practice management system.

Dr. dent. med. Jure Robičverified

Greater efficiency and full confidence in our sterilization process ⭐⭐⭐⭐⭐

Since introducing MELAG autoclaves, our sterilization workflow has become significantly faster and more predictable. The devices run reliably; cycles are stable, and results consistently meet the highest hygiene standards. This gives our team complete confidence in patient safety.

DentOP Clinic, Bucharestverified

This reliable autoclave successfully supports our intense activity.

Our implant clinic requires strict sterilisation protocols. MELAG's Vacuclave 550 was the solution to the high volumes of sterilised instruments we need on a daily basis. Thanks to its larger sterilisation chamber, we can now sterilise more instruments, more quickly. This reliable autoclave successfully supports our intense activity.

DENTALIST Clinic, Bucharestverified

Vacuklav 44 B+ suits our high sterilization standards perfectly.

The safety of our patients is our top priority. With the expansion of our business and clinic, we needed a reliable, high quality autoclave that could support our growth. Dexellence recommended the Vacuklav 44 B+, which is perfectly suited to our high sterilisation standards.

Teaserimage what is a large steam sterilizer

What is a large steam sterilizer?

International standards prescribe that large steam sterilizers have a minimum chamber volume of 60 litres or sufficient space for one or more sterilization units. A sterilization unit (STU) is a module with the dimensions 300 x 300 x 600 mm (h x w x d). The high capacity of these steam sterilizers is needed by a central sterile services department (CSSD), also called sterile processing department (SPD) or central supply department (CSD) as an integrated part of hospitals and other larg practices and clinics that performs reprocessing of medical devices, equipment and instruments.